The MTB Portal Interprets Cancer Genomic Variants

This is a research version of the MTB Portal that provides a general framework for interpreting the functional and predictive relevance of a given list of gene variants through interactive reports .

The MTB Portal uses distinct levels of supporting evidence

Variants are annotated using multiple knowledgebases , bona fide biological assumptions and computational prediction models .

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The MTB Portal follows clinical expert consensus

The variant annotation is based on established expert agreement .

About us

This is an open version of the MTB Portal that provides a general interpretation of a user-submitted list of cancer gene variants. The Portal integrates multiple computational tools and databases, which are referenced and linked, where appropriate. These resources are openly available for research purposes but may require a separate license for other uses.
The open version of the MTB Portal is strictly limited to academic research use. Access and use of the open version of the MTB Portal implies acceptance of these terms. When using the MTB Portal, please cite: Tamborero D, Dienstmann R et al. Nature Medicine 2020 and/or Tamborero D et al. Nature Cancer 2022 .